Orbitrap ID-X – Tribrid Mass Spectrometer System

The Thermo ScientificTM Orbitrap ID-XTM TribridTM Mass Spectrometer combines industry-leading mass analyzer technology dedicated for small molecule analysis with the Thermo ScientificTM AcquireX intelligent MSn data acquisition strategy, to collect more meaningful data.

By capturing more low-abundance analytes and leveraging streamlined data analysis and mass spectral prediction tools, the system's intuitive, automated workflow accelerates results to let you go beyond faster.


תיאור

Unique Features & Benefits of the Orbitrap ID-X MS:

Focus on your science, not on instrument setup

Profile your complex samples with the combination of Thermo ScientificTM TribridTM architecture, method editor templates and ready-to-use experimental parameters, which enable you to efficiently acquire data without the need for extensive user expertise.

Collect more meaningful data, not just more data

Increase profiling efficiency by automating MSn data acquisition methods with the intelligent Thermo Scientific AquireX data acquisition tool, and attain a higher number of compounds with distinguishable fragmentations that can be further analyzed.

Speed, simplicity, and flexibility that match your analysis

Produce information-rich MSn data on complex samples enabling fast, automated data processing. Using a comprehensive, integrated set of data analysis tools, extract high-confidence results from complex data.

Demystify unknowns with MSn data
Identify knowns and unknowns with confidence, and elucidate structures of unknowns with LC/MS-based tools for structural elucidation, including MSn mass spectral trees, in-silico fragmentation, and precursor ion fingerprinting.

Performance Characteristics of the Orbitrap ID-X MS:

Mass range:

m/z 50–2,000

Orbitrap mass analyzer resolution:

7,500–500,000 (FWHM) at m/z 200

Scan rate:

Orbitrap mass analyzer MSn up to 30 Hz
Ion trap MSn up to 40 Hz

Mass accuracy:

<3 ppm RMS using external calibration
<1 ppm RMS using internal calibration

MS/MS electrospray ionization (ESI) ion trap sensitivity:

2 μL of a 50 fg/μL solution of reserpine (100 fg total) injected at a flow of 500 μL/min will produce a minimum signal-to-noise ratio of 100:1 for the transition of the isolated protonated molecular ions at m/z 609 to the largest two product ions, m/z 397 and m/z 448, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, m/z 165–615. The test requires the HESI probe.

Dynamic range:

>5,000 within a single scan

MS scan power:

MSn, for n = 1 through 10

Multiplexing using ion-routing multipole:

Up to 10 precursors per scan using the quadrupole mass filter for targeted MS2 and Selected Ion Monitoring (SIM)

Polarity switching:

One full cycle in 1.1 sec (one full scan in positive mode and one full scan in negative mode at a resolution setting of 30,000)

יצרן: Thermo Scientific

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