The Thermo ScientificTM Q ExactiveTM hybrid quadrupole-Orbitrap mass spectrometer introduced the revolutionary concept of QuanfirmationTM: the ability to routinely and confidently identify, quantify, and confirm in a single analysis using a single mass spectrometer.
The Thermo ScientificTM Q ExactiveTM Plus takes Quanfirmation to a new level with increased performance meeting applied markets requirements.
Technical enhancements to the original Q Exactive instrument maximize performance and reliability for large- and small-molecule applications. Advanced quadrupole technology (AQT) optimizes precursor selection and transmission, improving quantitation of low-abundance ions in the most complex matrices. Sophisticated data-independent analysis (DIA) and parallel reaction monitoring (PRM) provide reproducible quantitation results while delivering complete qualitative confidence.
An optional Protein Mode enhances analysis of intact proteins through sophisticated ion beam control and easy pressure adjustment, while optional 280,000 maximum resolution ensures maximum ID confidence in top down and Lipidomics as well as in small molecule applications. The implementation of the Advanced Active Beam Guide is an intelligent ion beam management for high flux ion sources, which ensures the reliability and accessibility needed for every day operation.
Unique Features of the Q Exactive Plus:
Characterize, quantify and confirm with unmatched confidence using the Q Exactive Plus mass spectrometer.
Performance Characteristics of the Q Exactive Plus:
Mass Range:
m/z 50-6,000
Max Resolving Power:
140,000 @ m/z 200 (280,000 optional)
Max Scan Rate:
Up to 12 Hz at resolution setting of 17,500 @ m/z 200
Mass Accuracy:
Internal: < 1 ppm RMS
External: < 3 ppm RMS
under defined conditions
Dissociation:
In-Source CID, HCD
Scan Functions:
FS, AIF, SIM, PRM, DIA, ddHCD
Quad Isolation
Step-less from full mass range down to 0.4 amu
Polarity Switching:
One full cycle in < 1 sec (one full scan positive mode and one full scan negative mode at resolution setting of 35,000)
Multiplexing:
Up to 10 precursors/scan
Analog Inputs:
One (1) analog input (0 – 1 V)
One (1) analog (0 – 10 V)
Options:
Intact Protein Mode, Enhanced Resolution Mode
יצרן: Thermo Scientific
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