Advancer

Batch microwave synthesizer for the scale-up of organic synthesis.

Batch format microwave synthesizer
Specifically designed so that methods developed in Biotage lab-scale systems can be safely and predictably transferred to a larger scale without re-optimization. Powerful mechanical stirring (up to 1000 rpm) In addition to homogeneous reactions, the system also supports heterogeneous reactions and the use of solid catalysts, heavy slurries and crystallizing products.

Flash Cooling^TM
The patent pending, "instant", adiabatic cooling promotes high purity and yield. For example, 200 mL of EtOH can be cooled from 180 °C to 65 °C in just 30 seconds.

Efficient heating
Powerful (0-1200 W) focused magnetron rapidly heats large volumes. Dynamic Field Tuning^TM minimizes reflected microwave energy.

Extra vessel entry ports
Allows in-situ sampling during run, addition of reagents (better control of exothermals), or the creation of inert atmospheric conditions. Adaptable for real-time reaction monitoring through e.g. Raman spectroscopy.

Best-in-class safety features
Breech lock closure with pressure release valve and automated safety interlock, ensure maximum operator safety. System pressure control rated up to 20 bar.